APIs with an Appetite

An appetite for understanding appetite

I have a sweet tooth, and I will always choose any pastry over spinach salad. I also know that many readers will share this preference. However, I am also aware that an unbalanced diet, in quantity and quality, is associated with serious health problems, including type 2 diabetes, metabolic syndrome, cardiovascular diseases, and cancer. It has therefore become a pressing question in basic and t...

Endocannabinoids: an appetite for fat.

I t has been known for decades that marijuana causes the “munchies,” i.e., a hunger for palatable food, and for more than 10 y that endocannabinoids (eCBs), in some ways marijuana’s counterpart in the organism, are orexigenic mediators (1). When injected in the hypothalamus (HT) or nucleus accumbens (NAc), two key brain areas for the homeostatic and hedonic control of food intake, these compoun...

Mechanisms concerned with appetite.

1. Newman, H. H., Freeman, F. N., and Holzinger, K. J. : Twins: A Study of Heredity and Environment. Chicago, Univ. Chicago Press, 1937. 2. Von Verschuer, 0. : Die vererbungsbiologische Zwillings-forschung. Ergebn. inn. Med. u. Kinderh., 31 :35, 1927. 3. Bauer, J. : Constitutio.i and Disease, 2nd Ed. New York, Grune & Stratton, 1945. 4. Ronv, H. R. : Obesity and Leanness. Philadelphia, Lea, 194...

An 11-year-old boy with emesis, decreased appetite, fever.

This 11-year-old boy was well until 2 weeks before admission, when he developed emesis, decreased appetite, and low-grade fever. One week before admission, he was seen by a physician and diagnosed with “stomach fl u.” However, a heart murmur was heard, and it was noted that his pulse was 140 bpm, and his blood pressure was 100/60. He had no outpatient testing at that time. Two days later, he ha...

Prednisolone as an appetite stimulant in patients with cancer.